The research conducted by the Department of Integrative Physiopathology and Therapy focuses on the multiscale study of the molecular mechanisms that control various diseases, using everything from cell lines and primary human cells to animal models and clinical samples. Its approach is translational, combining basic and preclinical research with samples from patients and donors. Our goal is to identify key factors, mechanisms of action, and therapeutic targets for treating diseases related to metabolic and immune stress, neuropathies, and degenerative pathologies associated with ageing, such as retinopathies. In addition, we seek to develop pharmacological, cellular and gene therapies, as well as biomarkers with diagnostic and prognostic value in diseases such as atherosclerosis, diabetes, liver fibrosis, epilepsy, Alzheimer’s, amyotrophic lateral sclerosis and degenerative disorders of the retina, also including aspects of women’s health such as menopause.
