DECODE: Discerning the mEchanisms of stem cell protection against COgnitive DEcline in paediatric brain tumours

Description

The DECODE project investigates how cell-based therapies protect the brain in children with brain tumors treated with radiotherapy, with the goal of preventing or reducing treatment-associated cognitive decline. In particular, it focuses on uncovering the immune mechanisms, especially involving the complement system, through which cellular products exert neuroprotective effects against radiation-induced brain inflammation and damage, ultimately aiming to improve long-term neurocognitive outcomes in pediatric cancer survivors.

Project investigators

• Vivian Capilla González – Principal Investigator
• Laura Pérez Alós – Principal Investigator

Funding entities

European Commission